The technology of the team is that we have developed a supra-active FIX molecule called FIX-TripleL. Combining our self-owned global patented FIX-TripleL technology with AAV-8 vector, we have completed POC and validated the therapeutic efficacy of FIX-TripleL in gene therapy using a hemophilia B mouse model. FIX-TripleL is therapeutically effective when used at a supra-low dose, as low as 50 times less than what has currently been used in hemophilia B gene therapy trials. Lowering viral doses is the emerging goal of gene therapy. FIX-TripleL, having extremely high activity, shows powerful potential in the market for hemophilia B gene therapy. In addition, the team is about to complete the GLP toxicology test and safety assessment under the grant supported by the Ministry of Science and Technology, Executive Yen, Taiwan. Taken together, the team's technology will become the first gene therapy clinical product that is entirely accomplished by Taiwan from development, mass production to GLP testing.